Diabetic Corneal Neuropathy

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Assessing diabetic neuropathy using corneal confocal microscopy.

N europathy is a frequent complication of diabetes and is a major cause of morbidity and mortality, potentially affecting distal sensory, motor, and autonomic nerves. Sequelae of diabetic neuropathy (DN) include foot ulceration, which can lead to the devastating consequence of lower limb amputation. Accurate and timely detection, characterization, and quantification of DN are critical in order ...

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Corneal Sensitivity as a Potential Marker of Diabetic Neuropathy.

Diabetes mellitus (DM) is a complex and chronic metabolic disorder leading to many complications. One of the most common complications of DM is diabetic neuropathy. There are many studies exploring corneal sensitivity as a potential marker of diabetic neuropathy. This review aims to explore association between corneal sensitivity and diabetic neuropathy. In diabetic neuropathy, corneal sensitiv...

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Corneal nerve tortuosity in diabetic patients with neuropathy.

PURPOSE Corneal confocal microscopy is a reiterative, rapid, noninvasive in vivo clinical examination technique capable of imaging corneal nerve fibers. Nerve fiber tortuosity may indicate a degenerative and attempted regenerative response of nerve fibers to diabetes. The purpose of this study was to define alterations in the tortuosity of corneal nerve fibers in relation to age, duration of di...

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Corneal Confocal Microscopy as a Measure of Diabetic Neuropathy

Distal symmetric polyneuropathy is the most common pattern of nerve injury in patients with diabetes (1,2). In fact, up to 50% of patients with diabetes will develop distal symmetric polyneuropathy at some point during their illness (3). Currently, the only effective treatment to prevent this prevalent condition is glucose control (4). Unfortunately, demonstrating an improvement in neuropathy o...

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Diabetic neuropathy.

Diabetic neuropathy affects up to 60 percent of the estimated 13 million Americans who have diabetes mellitus. Foot and ankle complications are responsible for more hospital admissions than all other complications of diabetes mellitus combined. Neuropathy is more likely to affect patients who have higher degrees of hyperglycemia and a longer history of diabetes, and those who are older, taller ...

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ژورنال

عنوان ژورنال: Journal of Clinical Medicine

سال: 2020

ISSN: 2077-0383

DOI: 10.3390/jcm9123956